Proposal Guidelines
This proposal booking system is used to request time on the Titan Krios electron microscopes and 950 MHz NMR spectrometer, at the Astbury Biostructure Laboratory, University of Leeds.
The facilities within the Astbury Biostructure Laboratory are primarily intended for use by Leeds researchers and their collaborators. However, we welcome applications from all potential users, both academic and industrial, as up to 20% of the time on our instruments can be made available to external users at the discretion of the Biostructure Lab management.
All users, but particularly external applicants, are encouraged to contact the support scientists for the relevant facility before submitting an application.
For more information, please visit the Astbury Biostructure website.
Before submitting a proposal, please ensure you read the relevant terms and conditions.
For electron microscopy, they can be found here.
Titan Krios Electron Microscopes
Who can apply?
- Researchers from across the University of Leeds.
- Academic or industrial scientists from other institutions who collaborate with Leeds.
- Academics from other institutions who want to request paid access.
- Users from industry who require paid access.
How do I apply for time?
- All users must submit a request for Titan Krios time via Aria.
- Supporting preliminary cryo data is required for all Titan Krios applications.
- Applications are considered by a user allocation group (UAG), which meets every four weeks. All instrument time is at the discretion of the panel.
- All users should expect a minimum of two weeks notice before their allocated time.
How far in advance do I need to apply for time?
- The schedule for Krioses is split into 28 day allocation periods. The UAG meets two weeks before each allocation period begins. Allocated time may be scheduled at any points during the 28-day allocation period.
- Users are encouraged to submit their proposal as soon as EM grids are ready.
- Unsuccessful applications for one allocation period will be rolled over into the next where appropriate.
- If rapid or extensive access is needed, users are encouraged to justify this on their proposal and directly contact the EM support scientist.
I don’t have preliminary cryo data, what should I do?
- Please contact the EM support scientist, Rebecca Thompson (r.f.thompson@leeds.ac.uk) for help in starting cryo-EM projects.
BioNMR
Bruker Ascend Aeon 950 MHz NMR Spectrometer
Who can apply?
- Researchers from across the University of Leeds.
- Academic or industrial scientists from other institutions who collaborate with Leeds.
- Academics from other institutions who want to request paid access.
- Users from industry who require paid access.
How do I apply for time?
- All users must submit a request for NMR time on the spectrometer via Aria.
- Supporting preliminary NMR data (1H, 1H-15N HSQC, etc.) is highly desired but not a requirement.
- Applications are considered by a user allocation group (UAG), which meets every four weeks. All instrument time is at the discretion of the panel.
- All users should expect a minimum of two weeks notice before their allocated time.
How far in advance do I need to apply for time?
- The schedule for the 950 NMR spectrometer is split into 28-day allocation periods. The UAG meets two weeks before each allocation period begins. Allocated time may be scheduled at any points during the 28-day allocation period.
- Unsuccessful applications for one allocation period will be rolled over into the next where appropriate.
- If rapid or extensive access is needed, users are encouraged to justify this on their proposal and directly contact the NMR support scientist.
I don’t have preliminary NMR data, what should I do?
- Please contact the NMR support scientist, Lars Kuhn (L.Kuhn@leeds.ac.uk) for help in starting NMR projects.