Instituto de Tecnologia Química e Biológica (ITQB NOVA) have
a call for a PhD researcher (contract up to 3 years) to work in a
multidisciplinary project at the interface of Structural Biology, Biochemistry
and Microbiology?
The project aims at the structural and functional characterization of
mycobacterial membrane enzymes involved in the biosynthesis of cell wall
components using a combined approach of X-ray
Crystallography and cryo- Electron Microscopy. It will also involve activity
assays to provide insights into the reaction mechanism of these glycosyltransferases,
synthesis of chemical compounds that may inhibit these enzymes, virtual screens,
docking and molecular simulations. This project is developed in close
collaboration with Filippo Mancia, Columbia University, NY, USA.
To learn more about this project please send an email to Margarida Archer (archer@itqb.unl.pt).
Academic Qualifications: PhD in Biological Sciences, Biochemistry or Structural Biology.
General admission requirements:
1) PhD in Biological Sciences, Biochemistry or Structural Biology;
2) Co-authorship in scientific articles;
3) Proficiency in English, written and spoken.
Specific admission requirements:
1) Experience in molecular biology tools, protein production and biophysical characterization;
2) Experience in X-ray Crystallography or cryo-Electron Microscopy;
3) Experience in supervision of students;
4) Experience in writing articles and managing scientific projects
Submission deadline for application: 1st March 2019 at 5pm GMT
Documents required in the application:
Detailled Curriculum vitae;
Motivation Letter;
Contact of two references;
PhD certificate
All documents must be sent as a single PDF file by email to concursos@itqb.unl.pt indication reference 30421-07-2018-FCT in the subject line.