Fixed term for 3 years (with possible extension to 4 or 5 years subject to funding), available from 1 November 2013, or as soon as possible thereafter
ERC Advanced Grant “Amyloid Fibril Cytotoxicity: New Insights from Novel Approaches”
Applications are invited for an ERC-funded postdoctoral research assistant to join a dynamic, interdisciplinary team focusing on the use of structural and cell biological methods to investigate the molecular mechanisms of protein aggregation into amyloid fibrils in vitro and the effects of aggregated/disaggregated species on cellular homeostasis. This large programme involves collaboration between the groups of Professor Sheena Radford and Drs David Brockwell, Neil Ranson, Eric Hewitt and Prof Alison Ashcroft within the Astbury Centre for Structural Molecular Biology. Ultimately, the programme of research will involve the appointment of four post-doctoral fellows.
We are now seeking a post-doctoral research assistant with skills in cryo-electron microscopy/tomography to join this team. You will focus on the use of cryo-electronmicroscopy/tomography, and super-resolution light microscopy to study the structure of amyloid aggregates and the interactions they make with biological membranes. You will join an integrated, well-funded team of three post-doctoral fellows who will use Protein Chemistry, Dynamic Force Spectroscopy and Cell Biology (already appointed) to achieve our project aims.
You should have (or be close to completing) a PhD in structural molecular biology, biophysics, or a related discipline. Expertise in cryo-electron microscopy is essential.
University Grade 7 (£30,424 – £36,298 p.a.)
Informal enquiries may be made to Professor Sheena E Radford, email s.e.radford@leeds.ac.uk or Dr Neil Ranson, email n.a.ranson@leeds.ac.uk
Closing Date: 16 October 2013
Ref: FBSMB0020
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