View All Mass Spectrometry at Instruct
The Proteomics core facility at CEITEC Instruct centre provides the academic and other entities with access to advanced proteomic technologies based on shared resources and the know-how of highly trained staff. Effective utilization of the state-of-the-art mass spectrometric instrumentation promotes understanding proteome complexity according to the demands of research community. Thus, the facility is involved in broad range of projects requiring protein characterisation covering fields of biochemistry, molecular and structural biology, human and veterinary medicine, microbiology, plant, agriculture and food sciences. The facility staff can offer a complete mass spectrometry-assisted proteomics services including sample preparation, separation of protein/peptide mixtures, qualitative and quantitative characterisation of proteins and their modifications by mass spectrometry and data processing.
More information can be found on the Proteomics core facility webpage.
At present, we operate a set of mass spectrometers which allow us to cover wide range of proteomic applications:
MALDI-TOF/TOF MS:
LC-MS/MS systems:
The core facility operates in a full service mode. The services cover all of the steps of mass spectrometry-based proteomic analyses from protein isolation, protein and peptide mixture separation (liquid chromatography, gel electrophoresis), to protein characterisation by mass spectrometry and data processing. We also provide consultations and basic training in proteomics.
Long-term cooperation in the field of proteomic applications (beyond the terms of CF services) we can provide via cooperative projects with our proteomic research group.
We cover all steps of proteomic analysis - protein isolation, separation of protein mixtures, protein characterization by mass spectrometry and bioinformatics data processing.