The laboratories of Young-Sam Lee and Gregory Bowman at Johns Hopkins University are seeking a highly motivated and productive scientist to study the structure and allosteric mechanisms of pyruvate kinase. This postdoc position will investigate recent observations that a metabolic intermediate called SAICAR can stimulate pyruvate kinase activity in cancerous cells, which is important for cell survival in nutrient poor conditions (see Keller et al., 2012, Science;)
The ideal candidate will have experience and a track record of success in biochemistry and protein crystallography. The position is available immediately, with funding available for two years at the standard NIH stipend levels. Please send CV and three references to gdbowman@jhu.edu and ylee99@jhu.edu. Applications will be reviewed until the position is filled.
